Abstract #2229

Cross-sectional robustness of 6 freely available software packages for brain volume measurements in multiple sclerosis

David Rudolf van Nederpelt¹, Houshang Amiri^1,2, Amanda Mariyampillai¹, Iman Brouwer¹, Samantha Noteboom³, Frederik Barkhof^1,4, Joost P.A. Kuijer¹, and Hugo Vrenken¹

¹Radiology and nuclear medicine, Amsterdam UMC, location VUmc, Amsterdam, Netherlands, ²Neuroscience research center, Kerman University of Medical Sciences, Kerman, Iran (Islamic Republic of), ³Anatomy and Neurosciences, Amsterdam UMC, location VUmc, Amsterdam, Netherlands, ⁴Institutes of Neurology and Healthcare Engineering, UCL London, London, United Kingdom

Synopsis

Automated segmentation of brain MR images has paved the way for large cohort atrophy studies in multiple sclerosis (MS). A variety of automated software packages is available. Here we aimed to quantify brain volume differences measured by six freely available software packages on data from 21 MS patients all scanned thrice on three different MR scanners. While intra-class correlation coefficients were high, systematic differences between scanners were found for every software. This suggests that direct comparison of volumes acquired with different scanners is not possible and standardization is needed.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.