The goal of this study was to better detect cyclic motion with multiple frequencies in tissue. A novel MRE technique was developed using motion encoding gradient (MEG) pulses of multiple scales (multi-scale MRE). These MEG pulses were designed and timed to approximate a complete basis of Haar wavelet system. Our hypothesis was that a set of orthogonal MEG pulses can capture the tissue motion more efficiently and tissue motion can be reconstructed by a simple inverse transform. Initial tests were performed on a phantom and a volunteer.
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