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Abstract #2274

7T resting state connectivity applied to HIFU procedures for planning and efficacy

Mark Lowe1, Jian Lin1, Ajay Nemani1, Sean Nagel2, and Stephen Jones1
1Imaging Institute, Cleveland Clinic, Cleveland, OH, United States, 2Neurosurgery, Cleveland Clinic, Cleveland, OH, United States


High Intensity Focused Ultrasound (HIFU) in now entering clinical practice, for example to treat essential tremor by causing small lesions in the thalamus. Due to small size of treatment lesions, treatment success depends critically on targeting, which is classically done using measurements and landmarks. We explore an alternative method using functional imaging to guide targeting, specifically using 7T resting state connectivity. We present preliminary data of the patterns of connectivity possible with 7T using a concatenated series of 18 healthy subjects.

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