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Abstract #2286

Isotropic resolution volumetric liver T2 mapping using a free-breathing navigator-gated radial stack-of-stars T2-prepared Dixon acquisition

Mark Zamskiy1, Kilian Weiss2, Felix N. Harder1, Stefan Ruschke1, Marcus R. Makowski1, Rickmer F. Braren1, and Dimitrios C. Karampinos1
1Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany, 2Philips GmbH Market DACH, Hamburg, Germany

Synopsis

Volumetric liver T2-mapping is of interest in the characterization of focal lesions and diffuse disease but remains technically challenging due to respiratory motion. The present work introduces a novel T2-prepared (T2prep) radial stack-of-stars two-point Dixon gradient echo sequence (T2prep-SoS-Dixon-TFE) for achieving motion-robust 3D isotropic T2-mapping in navigator-gated scans using a B0/B1-insusceptible modified adiabatic BIR-4 RF-pulse for T2prep. T2-mapping is performed via dictionary matching to Bloch simulations for the Dixon-decomposed water signal. The proposed method enables motion-robust liver fat confounder-free volumetric T2 quantification in better agreement with MRS compared to GraSE and may improve the clinical applicability of free-breathing abdominal T2-mapping.

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