Articular Cartilage T2 Relaxation Time Decreases in Regions of Loaded Contact in Cadaver Knees
Natasha M. Bzowey1, Marianne S. Black2, Lumeng Cui3, Chelsey S. Thorson1, Madeline M. Martel1, and Emily J. McWalter1
1Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, SK, Canada, 2Department of Radiology, Stanford University, Stanford, CA, United States, 3Department of Biomedical Engineering, University of Saskatchewan, Saskatoon, SK, Canada
The aim of this work was to identify focal changes in T2 relaxation times inside and outside regions of tibiofemoral contact in loaded cadaver knee articular cartilage. We used a cluster analysis approach to identify focal regions of change in T2 relaxation time. We found clusters of increased and decreased T2 relaxation time when the cartilage was loaded; the majority of the clusters of decreased T2 relaxation time were observed within the tibial and femoral cartilage contact area.
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