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Abstract #2302

Anisotropy of T2 and T Relaxation in Bovine Articular Cartilage at 3 T

Ville Kantola1, Jouni Karjalainen1, Tomi Jaakola1, Henri Leskinen2, Mikko Nissi1,2, Miika Nieminen1,3,4, and Victor Casula1,4
1Research Unit of Magnetic Imaging, Physics and Technology, University of Oulu, Oulu, Finland, 2University of Eastern Finland, Kuopio, Finland, 3Department of Diagnostic Radiology, Oulu University Hospital, Oulu, Finland, 4Medical Research Center, University of Oulu and Oulu University Hospital, Oulu, Finland


Multiple studies have investigated the orientation dependence of T2 and T relaxation in articular cartilage using ultra-high field magnets. This study aims to replicate these findings in a clinical measurement setting, performing a series of measurements at multiple orientations on a 3 T clinical scanner using large ex vivo joint samples. Function of a previously suggested relaxation model was confirmed in a low field-strength environment. Anisotropic components of T2 and T relaxation varied widely depending on the measured parameter, the spin-lock frequency, the magnetization preparation used for the spin-lock experiment (continuous wave/adiabatic), and the considered cartilage layer (superficial/deep half).

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