Multiple studies have investigated the orientation dependence of T2 and T1ρ relaxation in articular cartilage using ultra-high field magnets. This study aims to replicate these findings in a clinical measurement setting, performing a series of measurements at multiple orientations on a 3 T clinical scanner using large ex vivo joint samples. Function of a previously suggested relaxation model was confirmed in a low field-strength environment. Anisotropic components of T2 and T1ρ relaxation varied widely depending on the measured parameter, the spin-lock frequency, the magnetization preparation used for the spin-lock experiment (continuous wave/adiabatic), and the considered cartilage layer (superficial/deep half).
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