Meeting Banner
Abstract #2320

Tracking disease progression in mouse models of polycystic kidney disease with high resolution MRI and automated postprocessing

Florian Schmid1, Georgios Koukos1, Matt Sooknah1, Sanam Assili1, and Johannes Riegler1
1Calico Life Sciences, South San Francisco, CA, United States

Synopsis

We present an improved MRI acquisition and data processing pipeline to assess disease progression in mouse models of polycystic kidney disease. High-resolution anatomical T2 weighted images as well as T2 mapping are used to track changes in kidney volume, cyst burden and tissue composition. We established versatile deep-learning automatic kidney segmentation, trained on a range of kidney disease stages, animal models and image resolutions.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords