Correlation methods between X- ray phase contrast imaging, MRI and histology for the study of the nervous central system
Laura Maugeri1, Charles Nicaise2, Aleksandar Jankovski3, Emil Malucelli4, Alejandra Sierra5, Ali Abdollahzadeh5, Raimo A. Salo5, Giuseppe Gigli6, Federico Giove7, Alessia Cedola8, and Michela Fratini8
1CNR -Institute of Nanotechnology, Lecce Unit & Roma Unit, LECCE, Italy, 2URPhyM – NARILIS, Université de Namur, Namur, Belgium, 3NEUR division, Université catholique de Louvain (UCLouvain), Institute of NeuroScience (IoNS), Brussels, Belgium, 4Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy, 5A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland, 6CNR -Institute of Nanotechnology, Lecce Unit, LECCE, Italy, 7Museo Storico della Fisica e Centro Studi e Ricerche Enrico Fermi, Rome, Italy, 8CNR -Institute of Nanotechnology, Roma Unit, Rome, Italy
Many serious pathologies of the central nervous system (CNS) are related to anomalous development or damages to the vascular and neuronal networks. Here, we show our approach based on MRI/XPCT, XPCT/ HISTOLOGY combination in order to study neuronal and vascular alterations following a damage in mouse models.
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