Abstract #2333
Imaging ex-vivo cynomolgus monkey brain in 150 um isotropic resolution
Chungseok Oh1, Yu Gyeong Kim2,3, Jeongheon Park4, Youngkyu Song4, Chang-Yeop Jeon2, Kyung Seob Lim5, Jincheol Seo2, Jung Bae Seong2, Jee-Hyun Cho4, Youngjeon Lee2, Jongho Lee1, and Hyeong-Geol Shin1
1Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Korea, Republic of, 3Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, Korea, Republic of, 4Center for Research Equipment, Korea Basic Science Institute, Cheongju, Korea, Republic of, 5Futuristic Animal Resource & Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Korea, Republic of
Synopsis
Due to the small size of the cynomolgus brain, imaging the fine structures in the brain is a challenging task. In this study, a sample preparation method is suggested for imaging the ex-vivo cynomolgus monkey brain with sub-millimeter resolution in 7T MRI. Using the proposed method, we acquired 150 um isotropic resolution MR images for whole brain, and the fine structures in the cynomolgus monkey brain was observed.
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