Zebrafish have become a ubiquitous animal model for studying a range of diseases and conditions. Typically, these studies are conducted in transparent juvenal fish where optical imaging techniques can be used. However, this is more difficult in adult zebrafish, restricting their use in longitudinal studies. Brain pathology in adult zebrafish can be imaged by preclinical MRI. Administering gadolinium based contrast agents (GBCA), which can also reduce scanning time, can highlight brain abnormalities such as lesions. T1/T2 values have been reported for gadolinium treated fixed/sacrificed zebrafish, however, this has not been reported for live zebrafish.
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