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Abstract #2331

Open-source modular 3D printed platform for in-vivo MRI experiments in awake mice and anesthetized mice and rats

Zakia Gironda1, Mihály Vöröslakos2, Youssef Wadghiri3, Omid Yaghmazadeh4, and Leeor Alon3
1Radiology, NYU School of Medicine, NEW YORK, NY, United States, 2Neuroscience Institute, NYU School of Medicine, New york, NY, United States, 3NYU School of Medicine, New York, NY, United States, 4Neuroscience Institute, NYU School of Medicine, NEW YORK, NY, United States


Despite their costly nature, the inexactitude of design in off-the-shelf MRI animal holders translates to a fastidious setup, iso-center misalignment, and incorrect animal body positioning. Our open-source 3D-print design provides precise iso-center alignment and minimizes motion artifact using its various head fixing mechanisms. It ensures comfortable positioning for rats and mice during in-vivo anesthetized and awake animal scan acquisition. The modular holder parts enable the same design to be used with other imaging modalities with minimal intervention. The design is low cost, ensures reproducibility and time efficiency of setup.

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