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Abstract #2358

Measurements of composite signals with MR-based neuronal current imaging: one step closer to clinical application.

Milena Capiglioni1, Claus Kiefer2, and Roland Wiest2
1Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging, University of Bern, Bern, Switzerland, 2Institute for Diagnostic and Interventional Neuroradiology, Support Center for Advanced Neuroimaging (SCAN), Inselspital, Bern, Bern, Switzerland

Synopsis

We evaluated the performance of stimulus-induced rotational saturation contrast (SIRS) to assess the possibility of detecting neuronal currents. We analyzed composite signals with multiple frequencies to evaluate the ability of the technique to be used as a filter of spectral components. We conclude that the method can separate and distinguish frequency components and reconstruct the distribution of spectral components between individually acquired signals. These tests are the basis for moving towards the clinical application of this sequence to locate fields with frequencies associated with specific pathologies.

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