Morphology Enabled Dipole Inversion (MEDI) is an iterative reconstruction algorithm for Quantitative Susceptibility Mapping (QSM) that is effective in suppressing streaking artifacts by exploiting the magnitude image as a morphological prior. However, contiguous areas of dipole-incompatibility (such as noise) induce shadow artifacts whose spatial frequency components are not sufficiently regularized by the gradient based regularization in MEDI. Regularizing these spatially connected regions reduces shadow artifacts in Morphology Enabled Dipole Inversion based Quantitative Susceptibility Mapping reconstructions.
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