Abstract #2362

Isotropic QSM in seconds using super-resolution 2D EPI imaging in 3 orthogonal planes

Beata Bachrata^1,2, Steffen Bollmann^3,4,5, Günther Grabner^1,6,7, Siegfried Trattnig^1,2, and Simon Daniel Robinson^1,3,8

¹High Field Magnetic Resonance Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University Of Vienna, Vienna, Austria, ²Karl Landsteiner Institute for Clinical Molecular MR in Musculoskeletal Imaging, Vienna, Austria, ³Centre of Advanced Imaging, University of Queensland, Brisbane, Australia, ⁴University of Queensland, Centre for Innovation in Biomedical Imaging Technology, Brisbane, Australia, ⁵School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia, ⁶Department of Medical Engineering, Carinthia University of Applied Sciences, Klagenfurt, Austria, ⁷Department of Neurology, Medical University Of Vienna, Vienna, Austria, ⁸Department of Neurology, Medical University of Graz, Graz, Austria

Synopsis

We propose a method to generate a super-resolution QSM from three orthogonal 2D EPI acquisitions with anisotropic voxels. Using distortion correction and non-linear co-registration of the individual EPI images with thick slices, a super-resolution EPI image with isotropic voxels was generated and used to compute a QSM. The super-resolution 2D EPI susceptibility maps, as well as the susceptibility values within deep grey matter structures, showed close correspondence to a standard GRE QSM. The net acquisition time was, however, reduced from several minutes to several seconds, allowing QSM in problematic patient cohorts and clinical routine.

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