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Abstract #2370

COSMOS-Based Susceptibility Estimations: Accuracy Assessment and Comparisons of QSM and Multiple-Angle Acquisitions

Dimitrios G. Gkotsoulias1, Roland Müller 1, Torsten Schlumm1, Niklas Alsleben1, Carsten Jäger1, Jennifer Jaffe2,3, André Pampel1, Catherine Crockford2,3, Roman Wittig2,3, and Harald Möller1
1Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany, 2Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany, 3Tai Chimpanzee Project, Centre Suisse de Recherches Scientifiques en Cote d'Ivoire, Abidjan, Cote D'ivoire


Calculation Of Susceptibility through Multiple Orientation Sampling (COSMOS) is assessed comparing the optimal, a clinically feasible and multiple-orientation schemes. The optimal COSMOS estimation is used as a gold standard and is compared to the other schemes using the similarity index (SSIM), mean absolute error (MAE) and Pearson’s coefficient (PC). Further comparisons include Thresholded K-space Division (TKD) quantitative susceptibility mapping. For selected white-matter regions, linear regression is used to assess the similarities between the different estimations.

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