Abstract #2373

Observing hyperintensity region within substantia nigra in cynomolgus monkey

Chungseok Oh¹, Chang-Yeop Jeon², Jincheol Seo², Hyeong-Geol Shin¹, Sooyeon Ji¹, Seongbeom Park³, Soohwa Song³, Dong Hoon Shin³, Youngjeon Lee², and Jongho Lee¹

¹Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, ²National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Korea, Republic of, ³Heuron Co.,Ltd, Incheon, Korea, Republic of

Synopsis

In this study, a hyperintensity region within substantia nigra is explored in cynomolgus monkeys over a wide range of ages. This region is similar to that of humans, which is often called as a swallow tail sign in healthy subjects. This nigral hyperintensity appears consistently in SMWI, QSM, and T₂*-weighted images, particularly in aged animals.

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