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Abstract #2373

Observing hyperintensity region within substantia nigra in cynomolgus monkey

Chungseok Oh1, Chang-Yeop Jeon2, Jincheol Seo2, Hyeong-Geol Shin1, Sooyeon Ji1, Seongbeom Park3, Soohwa Song3, Dong Hoon Shin3, Youngjeon Lee2, and Jongho Lee1
1Department of Electrical and Computer Engineering, Seoul National University, Seoul, Korea, Republic of, 2National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Korea, Republic of, 3Heuron Co.,Ltd, Incheon, Korea, Republic of


In this study, a hyperintensity region within substantia nigra is explored in cynomolgus monkeys over a wide range of ages. This region is similar to that of humans, which is often called as a swallow tail sign in healthy subjects. This nigral hyperintensity appears consistently in SMWI, QSM, and T2*-weighted images, particularly in aged animals.

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