Abstract #2378

Quantitative Analysis of Deep Nuclei in Patients with Parkinson’s disease (PD) using STrategically Acquired Gradient Echo (STAGE) Imaging

Zhaoxi Liu¹, Yiwei Zhang², Han Wang¹, Dan Xu¹, Bo Wu³, E. Mark Haackeb⁴, Hui You¹, and Feng Feng¹

¹Peking Union Medical College Hospital, Bejing, China, ²Peking university first hospital, Bejing, China, ³SpinTech, Inc., Bingham Farms, MI, United States, ⁴Wayne State University, Detroit, MI, United States

Synopsis

Patients with Parkinson’s disease (PD) showed increased iron deposition in the substantia nigra, red nucleus, dentate nucleus and globus pallidus compared with healthy controls. Besides, the T1 value, T2* value and R2* value of deep nucleus also altered in PD patients. Which suggested the STrategically Acquired Gradient Echo (STAGE) imaging could provide a good performance in quantitative analysis in multi-modal parameters.

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