Abstract #2399

Reproducibility of MR Elastography Stiffness Measurements across Field Strength in Obese Adults

Nikolaos Panagiotopoulos^1,2, Danielle Batakis³, Tanya Wolfson⁴, Thekla Helene Oechtering^1,2, David T. Harris¹, Alan McMillan^1,5,6,7, Claude B. Sirlin³, and Scott B. Reeder^1,5,6,8,9

¹Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States, ²Department of Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, ³Department of Radiology, University of California San Diego, San Diego, CA, United States, ⁴Computational and Applied Statistics Laboratory, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA, United States, ⁵Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, ⁶Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, ⁷Department of Electrical and Computer Engineering, University of Wisconsin - Madison, Madison, WI, United States, ⁸Department of Medicine, University of Wisconsin - Madison, Madison, WI, United States, ⁹Department of Emergency Medicine, University of Wisconsin - Madison, Madison, WI, United States

Synopsis

MR elastography (MRE) allows for the quantification of liver stiffness as a quantitative biomarker of liver fibrosis. Between field strength reproducibility has been shown to be high in non-obese populations. Data in obese individuals are limited, however, and obese patients may benefit from early diagnosis as they have an increased risk of liver fibrosis. Therefore, in this work we examined the reproducibility of MRE measurements across field strength in a cohort of 34 obese adults. MRE based liver stiffness measurements were highly reproducible between field strengths. Technical success rate was nearly 100% in this challenging, but relevant population.

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