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Abstract #2399

Reproducibility of MR Elastography Stiffness Measurements across Field Strength in Obese Adults

Nikolaos Panagiotopoulos1,2, Danielle Batakis3, Tanya Wolfson4, Thekla Helene Oechtering1,2, David T. Harris1, Alan McMillan1,5,6,7, Claude B. Sirlin3, and Scott B. Reeder1,5,6,8,9
1Department of Radiology, University of Wisconsin - Madison, Madison, WI, United States, 2Department of Radiology and Nuclear Medicine, Universität zu Lübeck, Lübeck, Germany, 3Department of Radiology, University of California San Diego, San Diego, CA, United States, 4Computational and Applied Statistics Laboratory, San Diego Supercomputer Center, University of California San Diego, La Jolla, CA, United States, 5Department of Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 6Department of Biomedical Engineering, University of Wisconsin - Madison, Madison, WI, United States, 7Department of Electrical and Computer Engineering, University of Wisconsin - Madison, Madison, WI, United States, 8Department of Medicine, University of Wisconsin - Madison, Madison, WI, United States, 9Department of Emergency Medicine, University of Wisconsin - Madison, Madison, WI, United States

Synopsis

MR elastography (MRE) allows for the quantification of liver stiffness as a quantitative biomarker of liver fibrosis. Between field strength reproducibility has been shown to be high in non-obese populations. Data in obese individuals are limited, however, and obese patients may benefit from early diagnosis as they have an increased risk of liver fibrosis. Therefore, in this work we examined the reproducibility of MRE measurements across field strength in a cohort of 34 obese adults. MRE based liver stiffness measurements were highly reproducible between field strengths. Technical success rate was nearly 100% in this challenging, but relevant population.

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