Abstract #2414
The Digital Brain Bank, an open access platform for post-mortem datasets
Benjamin C. Tendler1, Taylor Hanayik1, Olaf Ansorge2, Sarah Bangerter-Christensen2, Gregory S. Berns3, Mads F. Bertelsen4, Katherine L. Bryant1, Sean Foxley1,5, Martijn P. van den Heuvel6,7, Amy F.D. Howard1, Istvan N. Huszar1, Alexandre A. Khrapitchev8, Anna Leonte2, Paul R. Manger9, Ricarda A.L. Menke1, Jeroen Mollink1, Duncan Mortimer1, Menuka Pallebage-Gamarallage2, Lea Roumazeilles10, Jerome Sallet10,11, Lianne H. Scholtens6, Connor Scott2, Adele Smart1,2, Martin R. Turner1,2, Chaoyue Wang1, Saad Jbabdi1, Rogier B. Mars1,12, and Karla L. Miller1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Division of Clinical Neurology, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 3Psychology Department, Emory University, Atlanta, GA, United States, 4Centre for Zoo and Wild Animal Health, Copenhagen Zoo, Copenhagen, Denmark, 5Department of Radiology, University of Chicago, Chicago, IL, United States, 6Department of Complex Trait Genetics, Centre for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, Netherlands, 7Department of Child Psychiatry, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands, 8Medical Research Council Oxford Institute for Radiation Oncology, University of Oxford, Oxford, United Kingdom, 9School of Anatomical Sciences, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 10Wellcome Centre for Integrative Neuroimaging, Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom, 11Stem Cell and Brain Research Institute, Université Lyon 1, INSERM, Lyon, France, 12Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands
Synopsis
We introduce the Digital Brain Bank (open.win.ox.ac.uk/DigitalBrainBank), a digital platform providing open access to curated, multimodal post-mortem neuroimaging datasets. Datasets span three themes; Digital Anatomist: datasets for neuroanatomical investigations; Digital Brain Zoo: datasets for comparative neuroanatomy; Digital Pathologist: datasets for neuropathology investigations. The first release includes 21 distinctive whole-brain diffusion MRI datasets, alongside microscopy and complementary MRI modalities. This includes one of the highest-resolution whole-brain human diffusion MRI datasets ever acquired, whole-brain diffusion MRI in 14 non-human primate species, and one of the largest post-mortem whole-brain cohort imaging studies in neurodegeneration. Our resource facilitates incorporating post-mortem data into neuroimaging studies.
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