Abstract #2461

Nonlinear multi-echo dipole inversion

Christian Kames^1,2, Jonathan Doucette^1,2, and Alexander Rauscher^1,2,3

¹UBC MRI Research Centre, University of British Columbia, Vancouver, BC, Canada, ²Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, ³Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada

Synopsis

We propose a two-pass multi-echo nonlinear dipole inversion method. In the first pass an initial susceptibility map is obtained. The susceptibility map is then further processed by deconvolving the residual of the forward computed phase and the input phase to recover remnant low frequency susceptibility sources. The proposed method attains a NRMSE of 18.8 on the QSM Reconstruction Challenge 2.0 calcification dataset (Sim2Snr1), decisively outperforming the best scoring submissions of the challenge (NRMSE 26.3, 28.3, 28.5).

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