Accumulation of gadolinium (Gd) following use of Gd-based contrast agents (GBCA) is a concern. To study the potential of T1 microscopy for assessing Gd residues in the kidney, rats were administered 8 intravenous doses of various GBCAs over a period of two weeks. Five days following the last administration, the kidneys were collected and fixed in formalin. High resolution T1 maps obtained from ex vivo scans showed significantly reduced T1 levels for both linear and macrocyclic GBCAs. This demonstrates to potential for quantitative T1 mapping to detect Gd residues non-invasively in renal tissue.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords