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Abstract #2493

Multiparametric MR imaging in diabetic nephropathy: New insights to evaluate early diabetic nephropathy noninvasively

Akira Yamamoto1, Tsutomu Tamada2, Yu Ueda3, Mitsuru Takeuchi4, Ayumu Kido2, Atsushi Higaki2, and Akihiko Kanki2
1Radiology, Kawasaki Medical School, Kurashiki, Japan, 2Kawasaki Medical School, Kurashiki, Japan, 3Phillips Japan, Tokyo, Japan, 4Radiolonet Tokai, Nagoya, Japan


The purpose of this study was to identify the changes in multiparametric magnetic resonance imaging (MRI) findings in early diabetic nephropathy (DN). Multiparametric measurements were made of the renal cortex and medulla. Significant differences were seen between the healthy and early DN (grade1) in optimal TI and inverted TI value. T2 value of cortex is in marginal significant (p=0.064). This study suggests the possibility that MRI using the values of optimal TI, inverted TI value and T2 value of cortex can be used to evaluate early diabetic nephropathy non-invasively and in a short period of time.

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