Chemical Exchange Saturation Transfer (CEST) imaging is a promising method for cancer imaging and was recently combined with MR fingerprinting (CEST-MRF) for fast quantitative relaxation and exchange mapping. The CEST-MRF parametric maps reflect different biophysical processes, and their combination provides a comprehensive picture of complex pathologies, like brain tumors. The goal of this work is to demonstrate the potential utility of CEST-MRF in imaging brain metastases (BM). The in vivo reproducibility of the method is quantified in a healthy subject and the clinical utility is shown in subjects with metastatic brain tumors.
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