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Abstract #2510

Tailored MR fingerprinting of pediatric brain tumor patients

Pavan Poojar1,2, Enlin Qian1, Alexis B Maddocks3, and Sairam Geethanath1
1Columbia Magnetic Resonance Research Center, Columbia University, New York, NY, United States, 2Dayananda Sagar College of Engineering, Bangalore, India, 3Columbia University Irving Medical Center, New York, NY, United States


We demonstrated the utility of tailored MR fingerprinting (TMRF) of pediatric patients with brain tumor to 1) differentiate tumor from healthy tissue using quantitative maps; 2) tailor TMRF sequence to include T2 fluid-attenuated inversion recovery (FLAIR) contrast that could potentially substitute T2 FLAIR sequence used in routine pediatric tumor protocol. The mean土SD difference in T1 and T2 values between tumor and normal tissues for 3 patients were 1.05土0.09 and 0.05土0.02 seconds respectively. The TR and flip angle trains were tailored to include T2 FLAIR contrast for adult imaging. Current and future work includes optimizing T2 FLAIR for the pediatric population.

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