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Abstract #2567

Classification of Gulf War Illness Patients vs Control Veterans Using fMRI Dynamic Functional Connectivity

Unal Sakoglu1, Amaresh Mishra1, Kaundinya S Gopinath2, Bruce A Crosson2, and Robert Haley3
1Computer Engineering, University of Houston-Clear Lake, Houston, TX, United States, 2Emory University, Atlanta, GA, United States, 3University of Texas Southwestern Medical Canter at Dallas, Dallas, TX, United States

Synopsis

Around 200,000 veterans suffer from Gulf War Illness (GWI). GWI is characterized by multiple deficits in cognitive, emotion, somatosensory and pain domains. In this study we studied 23 GWI patients and 30 age-matched control veterans with resting-state fMRI in order to classify patients versus controls using dynamic functional connectivity among brain networks. Results show that different brain networks have discriminating power, pointing to widespread impairments in functional connectivity of visual, semantic, multi-sensory, and sensory-motor processing networks in GWI, consistent with multi-symptom nature of GWI.

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