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Abstract #2582

Combination of IVIM with DCE-MRI in diagnostic and prognostic evaluation of breast cancer

Yurong zheng1, Li Li1, Rui Wang1, Tiejun Gan1, Pengfei Wang1, Jing Zhang1, and Kai Ai2
1Department of Magnetic Resonance, LanZhou University Second Hospital, Lanzhou, China, 2Philips Healthcare, Xi’an, China


Intravoxel incoherent motion (IVIM) combined with Dynamic Contrast Enhanced MRI (DCE-MRI) are meaningful MRI techniques applied to breast cancer. This study uses DCE-derived parameters (voiume translocation constant, Ktrans and rate constant, Kep) and IVIM-derived parameters (diffusion coefficient, D and perfusion fraction, f) to perform correlation analysis with prognosis of breast cancer indexes (ER, PR, her-2, Ki-67). The results show that IVIM and DCE-MRI can distinguish benign and malignant breast lesions. Therefore, there are correlation between Ktrans, Kep, D and prognostic factors of breast cancer. Our research may provide more important clinical evidence for the treatment and prognosis of breast cancer.

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