This study compared the image quality of single-shot echo-planar imaging (ss-EPI) and readout-segmented echo-planar imaging (rs-EPI) in cervical cancer (CC). ADC values derived from these two sequences were considered as diagnostic capabilities for CC’s lymph-vascular space invasion (LVSI) and lymph node metastasis (LNM). The results showed that rs-EPI images of cervical cancer had higher subjective image quality scores, lower SNR, but no difference in CNR and ADC values. ADC was able to predict the CC’s LNM status，but couldn’t identify the LVSI status. ADC of rs-EPI sequence was superior to diagnose CC’s LNM status.