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Abstract #2591

Searching for an MR Fingerprinting sequence to measure brain oxygenation without contrast agent

Thomas Coudert1, Aurélien Delphin1, Jan M Warnking1, Benjamin Lemasson1,2, Emmanuel Luc Barbier1, and Thomas Christen1
1Univ. Grenoble Alpes, Inserm, U1216, Grenoble Institut Neurosciences, GIN, Grenoble, France, 2MoGlimaging Network, HTE Program of the French Cancer Plan, Toulouse, France


We propose to use numerical simulations and Monte Carlo approaches to test 40 MR fingerprinting sequences for their ability to quantify the BOLD effect and provide maps of baseline blood oxygen saturation without the need for contrast agent injection. Our results suggest that several sequences can produce SO2 maps with less that 3% error on average even in the presence of B1 and B0 inhomogeneities. T2 and blood vessel radius could also be estimated with the same acquisitions.

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