Abstract #2650

Amide proton transfer imaging for differentiation of glioblastoma from brain metastasis

Utarat Kaewumporn¹, Doonyaporn Wongsawaeng¹, Siriwan Piyapittayanan¹, Chanon Ngamsombat¹, Panid Chaysiri¹, Janiya Kittikornchaichan¹, Kritdipha Ningunha², Nanthasak Tisavipat², Titima Itthimathin², Ketkanok Rayaroji², and Orasa Chawalparit¹

¹Radiology, Faculty of Medicine Siriraj hospital, Mahidol University, Bangkok, Thailand, ²Bangkok International Hospital, BDMS, Bangkok, Thailand

Synopsis

Until now, the differentiation between glioblastoma and brain metastasis still has some limitations and inconclusive findings.

This study aimed to use amide proton transfer (APT)-weighted imaging to differentiate glioblastoma from brain metastasis.

We found that by quantitative assessment, the APTw value in enhancing solid portion and peritumoral high FLAIR area of glioblastomas were significantly greater than that of brain metastases. The APTw color map also showed higher signal at the peritumoral high FLAIR area in glioblastomas than metastasis by visual assessment.

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