Abstract #2671

Ex vivo 7T MRI of resection specimen of oral cancer to improve margin control.

Klijs J. de Koning¹, Rob Noorlag¹, Annette van der Toorn², Gerben E. Breimer³, Jan Willem Dankbaar⁴, Remco de Bree¹, and Marielle E.P. Philippens⁵

¹Head and Neck Surgical Oncology, University Medical Center Utrecht, Utrecht, Netherlands, ²Biomedical MR Imaging & Spectroscopy Group, University Medical Center Utrecht, Utrecht, Netherlands, ³Pathology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Radiology, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands

Synopsis

We validated the measured resection margins of the surgical specimens of tongue carcinoma on 7T ex vivo MRI with histopathology using T2 weighted MRI. In 3D T2wTSE (250 μm³) with an acquisition time of 15-20 minutes, the resection margins was undestimated by 0.5 mm (+/- 1.3 mm). This will be developed into a clinical study with immediate re-resection during surgery to prevent adjuvant (chemo)radiotherapy, which is associated with radiation induced side effects.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.