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Abstract #2670

Application of Fast Field-Cycling (FFC) NMR relaxometry in Colorectal Cancer

Amnah Alamri1, Lionel Broche1, and Leslie Samuel2
1Aberdeen Biomedical Imaging Centre, Aberdeen, Scotland, 2Aberdeen Royal Infirmary, Aberdeen, Scotland


This pilot study was performed to compare healthy and colorectal cancer samples by investigating R1 NMRD profiles acquired with Fast Field-Cycling (FFC) NMR relaxometry. We collected samples from 18 patients and found a significant difference (P=0.001) in the relaxation rates between normal and colorectal cancer tumours below 100 kHz (2.3uT), while this difference became smaller with increasing the magnetic field strengths and disappeared above 1 MHz (23 uT). This dispersion profile may lead to great potential for diagnosis, staging and monitoring treatment response.

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