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Abstract #2673

Longitudinal hybrid PET/MRI in juvenile-onset Huntington disease (joHD): a pilot study

Maria Eugenia Caligiuri1, Patrizia Vizza2, Pierangelo Veltri3, Francesco Cicone3, Paolo Barberio3, Giuseppe Lucio Cascini3, Eugenia Scaricamazza4, Sabrina Maffi4, Simone Migliore4, Ferdinando Squitieri4,5, and Umberto Sabatini3
1Neuroscience Research Center, University "Magna Graecia", Catanzaro, Italy, 2Mater Domini University Hospital, Catanzaro, Italy, 3University "Magna Graecia", Catanzaro, Italy, 4IRCCS Casa Sollievo della Sofferenza/CSS-Mendel, San Giovanni Rotondo/Rome, Italy, 5Italian League fo Research on Huntington (LIRH Foundation), Rome, Italy


Hybrid PET-MRI is an emerging technique that allows multimodal evaluation of brain structure and function. This study evaluates longitudinal PET-MRI in one patient with stage-2 joHD, to assess changes related to disease progression. This approach might be useful to test the efficacy of disease-modifying drugs.

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