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Abstract #2687

Demonstration of an end-to-end open-source pipeline for a spiral-based rs-fMRI sequence

Marina Manso Jimeno1,2, John Thomas Vaughan Jr.1,2, and Sairam Geethanath2
1Department of Biomedical Engineering, Columbia University, New York, NY, United States, 2Columbia Magnetic Resonance Research Center, New York, NY, United States


Spiral trajectories are suitable for fMRI as they provide high temporal resolution and motion tolerance. However, they are not typically available on scanners as the associated reconstruction is more involved. We have demonstrated the feasibility of an open-source spiral sequence end-to-end pipeline and compared it to the vendor-supplied EPI sequence. Although the spiral images showed signal loss near the frontal sinus, both datasets presented similar image quality and contrast. Importantly, the spiral sequence had a 2.3-fold advantage on temporal SNR and achieved analogous functional connectivity maps of the DMN, demonstrating the sequence BOLD sensitivity and viability.

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