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Abstract #2702

Nanoscopic materials for quantitative water exchange phantoms

Scott D. Swanson1, Dariya I. Malyarenko1, and Thomas L. Chenevert1
1Radiology, University of Michigan, Ann Arbor, MI, United States

Synopsis

Nanoparticle lipid vesicles are developed with controllable water exchange to provide a ground-truth benchmark for MR methods which measure exchange. Diffusion data are collected as a function of diffusion delay Δ. An exchange time, τ, is measured to be 164 ms in a phantom with a highly fluid membrane. These materials should help to clarify water dynamics in complex systems.

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