Abstract #2725

Soy lecithin: a phantom material for the adjustment of apparent diffusion coefficient in magnetic resonance imaging

Victor Fritz¹, Petros Martirosian¹, Jürgen Machann^1,2, and Fritz Schick^1,2

¹Department of Diagnostic and Interventional Radiology, University of Tuebingen, Germany., Section on Experimental Radiology, Tuebingen, Germany, ²Institute for Diabetes Research and Metabolic Diseases of the Helmholtz Centre Munich at the University of Tuebingen, Tuebingen, Germany

Synopsis

The aim of this work was to systematically investigate whether lecithin is suitable for the construction of a diffusion phantom that covers and simulates ADC-values occurring in human tissue. For this, aqueous solutions of different lecithin concentrations (0%-10%) were prepared and measured by DWI. The presented results showed that lecithin is a suitable agent for simulating a wide variety of ADC-values. Even low concentrations showed a strong decrease in the ADC-value of water. However, with increasing concentration, lecithin also showed a strong influence on T2, so that ADC and T2 cannot be set independently from one another in lecithin-based phantoms.

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