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Abstract #2790

Reproducibility of rapid quantitative multiparameter mapping using skipped-CAIPI 3D-EPI

Difei Wang1, Rüdiger Stirnberg1, and Tony Stöcker1,2
1German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany, 2Department of Physics and Astronomy, University of Bonn, Bonn, Germany


We investigated the reproducibility of multiparameter mapping (MPM) using multi-echo skipped-CAIPI 3D-EPI at 3T. Compared to >15 minutes of FLASH-MPM, EPI-MPM under 3 minutes achieved considerably high repeatability. In only one fifth of the total scan time of FLASH, the resulting CoVs of EPI were only 1.2-2.2 times larger than FLASH for R1, PD and MTsat, while the CoV of EPI for R2* was even smaller. Minor differences of the observed parameter estimates can be attributed to the intrinsic difference between EPI and FLASH sequence timing.

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