Abstract #2789

Test-retest repeatability of radiomic features derived from T2w MRI in prostate cancer patients

Barbara Daria Wichtmann¹, Steffen Albert², Daniel Pinto dos Santos³, Ulrike Irmgard Attenberger¹, and Bettina Baessler⁴

¹Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany, ²Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, ³Department of Radiology, University Hospital Cologne, Cologne, Germany, ⁴Institute of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Wuerzburg, Germany

Synopsis

Radiomics enables the extraction of quantitative features from medical images, potentially augmenting the characterization of healthy and diseased tissue. Before these features can be routinely used as biomarkers in clinical practice, however, their repeatability and reproducibility must be ensured. This study seeks to investigate feature repeatability in an in-vivo, clinical test-retest dataset of prostate cancer patients. Our results show that the majority (71.8%) of radiomic features extracted from in-vivo, clinical T2-weighted images was not repeatable, emphasizing the need for repeatability and reproducibility studies.

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