Test-retest repeatability of radiomic features derived from T2w MRI in prostate cancer patients
Barbara Daria Wichtmann1, Steffen Albert2, Daniel Pinto dos Santos3, Ulrike Irmgard Attenberger1, and Bettina Baessler4
1Department of Diagnostic and Interventional Radiology, University Hospital Bonn, Bonn, Germany, 2Computer Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany, 3Department of Radiology, University Hospital Cologne, Cologne, Germany, 4Institute of Diagnostic and Interventional Radiology, University Hospital Wuerzburg, Wuerzburg, Germany
Radiomics enables the extraction of quantitative features from medical images, potentially augmenting the characterization of healthy and diseased tissue. Before these features can be routinely used as biomarkers in clinical practice, however, their repeatability and reproducibility must be ensured. This study seeks to investigate feature repeatability in an in-vivo, clinical test-retest dataset of prostate cancer patients. Our results show that the majority (71.8%) of radiomic features extracted from in-vivo, clinical T2-weighted images was not repeatable, emphasizing the need for repeatability and reproducibility studies.
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