Impact of tract propagation stop criteria on skeletal muscle DTI fiber tract completeness and characteristics
Carly Anne Lockard1,2, Melissa T Hooijmans3, Xingyu Zhou2,4, and Bruce M Damon1,2
1Stephens Family Clinical Research Institute, Carle Health, Urbana, IL, United States, 2Carle Clinical Imaging Research Program, Carle Health, Urbana, IL, United States, 3Department of Radiology and Nuclear Medicine, Amsterdam Movement Sciences, Amsterdam University Medical Center, Amsterdam, Netherlands, 4Biomedical Engineering, Vanderbilt University, Nashville, TN, United States
Diffusion-tensor MRI tractography has been applied to characterize skeletal muscle architecture and diffusion characteristics. Ideally, tracking would occur completely for accurate length, angle, curvature, and diffusion property estimation of a bundle of fibers. In practice, it is desirable to end tracts early if poor quality data is encountered and tract termination settings can influence the balance between tract completeness and desirable exclusion of inaccurate tract regions. This work examines the effect of applying a range of fractional-anisotropy and intersegment-angle tract-termination thresholds on muscle architecture and diffusion estimates, and fiber polynomial fit residuals.
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