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Abstract #2841

Low-grade glioma resting-state fMRI pre-operative maps: a comparison with functional atlas from direct electrode stimulation.

Beatrice Federica Luciani1, Donna Gift Cabalo1, Francesca Saviola1, Luca Zigiotto2,3, Stefano Tambalo1, Domenico Zacà1, Lisa Novello1, Silvio Sarubbo2,3, and Jorge Jovicich1
1CIMeC Center for Mind/Brain Sciences, Trento, Italy, 2Department of Neuroscience, Division of Neurosurgery, S.Chiara Hospital, APSS Trento, Trento, Italy, 3Structural and Functional Connectivity Lab, S.Chiara Hospital, APSS Trento, Trento, Italy


A cortical-subcortical functional atlas has been recently proposed from direct-electrode stimulation on low grade glioma patients. The agreement between that atlas and non-invasive pre-operative resting-state functional MRI (rs-fMRI) data has not yet been investigated. In this study, we use pre-operative rs-fMRI data and the RestNeuMap tool to investigate the agreement between language and sensory networks in a group of low grade glioma patients. We find that rs-fMRI networks of language and speech arrest show greater overlap with DES-derived functional atlas than the sensorimotor network.

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