Abstract #2878

Acute Global Structural and Diffusivity Changes Following Treatment with MRgFUS

Kain Kyle^1,2, Yael Barnett³, Stephen Tisch³, Ben Jonker³, Arkiev D'Souza¹, Jerome Maller⁴, Michael Barnett^1,2, Joel Maamary³, and Chenyu Wang^1,2

¹University of Sydney, Sydney, Australia, ²Sydney Neuroimaging Analysis Centre, Sydney, Australia, ³St Vincent's Hospital Sydney, Sydney, Australia, ⁴GE Healthcare Australia, Melbourne, Australia

Synopsis

MRgFUS is a non-invasive procedure for the treatment of tremor, involving the application of high-energy ultrasound waves to ablate tissue in the brain in regions implicated in tremor networks. There is a lack of data on the acute changes outside the ablated region following treatment with MRgFUS. This investigation sought to examine changes in brain volume and diffusion tensor metrics following treatment with MRgFUS.

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