Three IVIM-DWI models to predict survival risk in laryngeal and hypopharyngeal squamous cell carcinoma patients after (chemo)radiotherapy
Ya Zhang1, Dehong Luo2, Wei Guo3, Zhou Liu2, Dan Bao1, Haijun Xu1, Lin Li1, Meng Lin1, Yanfeng Zhao1, and Xinming Zhao1
1Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medica, Beijing, China, 2Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Shenzhen, China, 3Radiology, Peking University Third Hospital, Beijing, China
To investigate the predicted survival risk power of three IVIM-DWI models in laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) patients after (chemo)radiotherapy, 45 patients were retrospectively enrolled. IVIM-DWI sequence scanning was performed using echo planner imaging (EPI) sequence with 12 b values (0, 10, 20, 30, 50, 70, 100, 150, 200, 400, 800 and 1000 s/mm2). Followed up for 2-72 months with median follow-up of 14 months. The pretreatment ADC, D, f value and D* value were significantly correlated with prognosis of local disease, and the pretreatment ADC, D* value were independent biomarkers for survival risk prediction.
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