Abstract #2895

Three IVIM-DWI models to predict survival risk in laryngeal and hypopharyngeal squamous cell carcinoma patients after (chemo)radiotherapy

Ya Zhang¹, Dehong Luo², Wei Guo³, Zhou Liu², Dan Bao¹, Haijun Xu¹, Lin Li¹, Meng Lin¹, Yanfeng Zhao¹, and Xinming Zhao¹

¹Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medica, Beijing, China, ²Radiology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Shenzhen, China, ³Radiology, Peking University Third Hospital, Beijing, China

Synopsis

To investigate the predicted survival risk power of three IVIM-DWI models in laryngeal and hypopharyngeal squamous cell carcinoma (LHSCC) patients after (chemo)radiotherapy, 45 patients were retrospectively enrolled. IVIM-DWI sequence scanning was performed using echo planner imaging (EPI) sequence with 12 b values (0, 10, 20, 30, 50, 70, 100, 150, 200, 400, 800 and 1000 s/mm2). Followed up for 2-72 months with median follow-up of 14 months. The pretreatment ADC, D, f value and D* value were significantly correlated with prognosis of local disease, and the pretreatment ADC, D* value were independent biomarkers for survival risk prediction.

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