Previously, we have proposed the method for characterizing the intra-voxel spatial distribution of apparent diffusion coefficients (ADC) by using texture analysis and showed that texture features can provide different information from the conventional diffusion tensor imaging. In this study, we extended our method to the apparent kurtosis coefficients (AKC). We compared the features of the intra-voxel spatial distribution of ADC with that of AKC. We found that there is no significant difference in the spatial distribution of AKC from that of ADC, and a short scanning time with a single b-value may be sufficient to obtain information on diffusion distribution.
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