Abstract #2911

A Novel Volume-Surface Integral Equation Formulation of Global Maxwell Tomography: Simulations and Experiments.

Ilias Giannakopoulos^1,2, Jose Seralles³, Jan Paska^1,2, Georgy Guryev³, Carlotta Ianniello^1,2, Luca Daniel³, Jacob White³, Ryan Brown^1,2,4, Daniel Sodickson^1,2,4, and Riccardo Lattanzi^1,2,4

¹Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, ²The Bernard and Irene Schwartz Center for Biomedical Imaging (CBI), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, ³Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁴Vilcek Institute of Graduate Biomedical Sciences, New York University Grossman School of Medicine, New York, NY, United States

Synopsis

Global Maxwell Tomography (GMT) is an inverse scattering technique that estimates electrical properties (EP) from magnetic resonance measurements. The original GMT relies on an approximation of the incident fields, which is not accurate for experiments, especially in-vivo. We propose a new GMT formulation, based on the volume-surface integral equation (VSIE) method, where we implicitly re-estimate the incident fields accounting for the updated EP in every GMT iteration. We show average EP reconstruction error below 8% for a uniform phantom experiment and below 10% for a simulation experiment with a heterogeneous head model and realistic SNR.

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