Abstract #2926
Design of Novel RF Pulse for Fetal MRI Refocusing Trains using Rank Factorization (SLfRank) to Reduce SAR and Improve Image Acquisition Efficiency
Sebastian Diaz1, Yamin Arefeen2, Borjan Gagoski3,4, Ellen Grant3,4, and Elfar Adalsteinsson2,5,6
1Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 2Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 3Department of Radiology, Harvard Medical School, Boston, MA, United States, 4Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, 5Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, 6Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, United States
Synopsis
Fetal MRI is inherently time-constrained due to unpredictable motion and comfort concerns. Single-shot spin-echo sequences address these concerns by rapidly acquiring images with desired tissue contrast. However, these sequences typically operate at specific absorption rate (SAR) limitations due to a train of refocusing pulses, which impose long TR times and reduce acquisition efficiency. This study leverages SLfRank, the use of ranked factorization to jointly solve for SLR bi-coupled spin parameters, to design refocusing profiles that reduce SAR while maintaining slice-profile performance. The proposed refocusing pulse reduced SAR by over 20% while producing similar image quality to the standard clinical sequence.
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