In MT imaging, particularly at ultra-high field, results can be influenced by spatial variations in both (1) on-resonance flip angle and (2) RF saturation specified by B1rms including on- and off-resonance contributions. Conventional pulse design with parallel transmission focuses on homogenizing flip angle (α) distributions but does not explicitly account for B1rms distribution.
In this work we propose a generalized pulse design framework that considers both α and B1rms and apply it to achieve uniform excitation and saturation at the same time. Performance is confirmed in phantom experiments at 7T, resulting in more uniform MTR compared to conventionally-designed pulses.
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