Abstract #2974

Application of MRI in tracking and evaluating of SPIONS labeled stromal stem cells transplanted in traumatic spinal cord injury of beagle

Xiaoli Mai¹, Jilei Zhang², Junting Zou¹, Yuanyuan Xie³, Bin Wang³, and Bing Zhang¹

¹Radiology Department, Nanjing Drum Tower Hospital, the affiliated hospital of Nanjing University Medical School, Nanjing, China, ²Philips Healthcare, Shanghai, China, ³Nanjing Drum Tower Hospital, Nanjing, China

Synopsis

Stromal cell transplantation plays an important role in the treatment of traumatic spinal cord injury (SCI). The multi-parameter MRI, including DTI, T2 , T2* mapping and QSM , of all beagles were performed before and after operation. We found that the transplanted stromal stem cells with Ruicun-labeled in the injured spinal cord could be quantified by QSM within 28 days after transplantation. FA value can be used to quantitatively evaluate the integrity of spinal fibers and the recovery of spinal nerve function. Thus, MRI can used to track the dynamic changes of SPIONS labeled stromal stem cells transplanted.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.