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Abstract #2984

7 T CBV fMRI reveal cortical microcircuits of bottom-up saliency in the human brain

Chengwen Liu1, Chen Liu2, Li Zhaoping3, and Peng Zhang2
1Second Xiangya Hospital,Central South University, Changsha, China, 2Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, 3University of T ╠łubingen, Max Planck Institute for Biological Cybernetics, T ╠łubingen, Germany


Using a slab-selective VASO sequence at 7 T, we investigate cortical depth-dependent CBV fMRI activity to orientation-defined saliency stimuli in early visual and parietal cortices of the human brain. Results show that the fMRI response of salient foreground bars is strongest in the superficial depth of V1, and peaks in the middle cortical depth of V2/V3 and IPS. These findings support the hypothesis that bottom-up saliency is initially created by iso-feature suppressions through lateral connections in V1 superficial layers, and then feedforward to parietal cortex to generate the attention priority map.

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