The structure-function coupling of aging brain
Hui Zhang1,2, Peng Cao1, Henry K.F. Mak2,3, and Edward S. Hui4
1Diagnostic Radiology, The University of Hong Kong, Pokfulam, Hong Kong, 2Alzheimer's Disease Research Network, The University of Hong Kong, Pokfulam, Hong Kong, 3The University of Hong Kong, Pokfulam, Hong Kong, 4Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong
We aim to investigate the effect of aging, sex, years of education, total cognition, and the disease burden of small vessel disease, the most cause of vascular dementia, on not only the coupling of the entire brain, but also the coupling of intra and inter-functional networks. We have demonstrated varying effect of sex, years of education and total cognition on global and intra/inter-network couplings.
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