With the help of 7T Imaging, we investigated the association between the thalamic anterior vascularization patterns and emotions, including depression and anxiety. Cerebral small vessel diseases were considered as a risk factor for emotional performance. The thalamic anterior vascularization pattern was found association with depression and anxiety in subjects without CSVD burden. In the CSVD group, the thalamic volume and cortex thickness in pars triangularis, rostral middle frontal and superior frontal were found significantly correlated with both HAMD and HAMA test scores. It suggests the pathway of the thalamus regulating emotion changes with the development of CSVD.
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