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Abstract #2999

Thalamus regulates emotional performance in different pathways with CSVD involved

Bei Wang1, Cen Guo2, He Wang1,3, Yan Han2, and Ying-Hua Chu4
1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China, 2Department of Neurology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China, 3Human Phenome Institute, Fudan University, Shanghai, China, 4MR Collaboration, Siemens Healthineers Ltd., Shanghai, China


With the help of 7T Imaging, we investigated the association between the thalamic anterior vascularization patterns and emotions, including depression and anxiety. Cerebral small vessel diseases were considered as a risk factor for emotional performance. The thalamic anterior vascularization pattern was found association with depression and anxiety in subjects without CSVD burden. In the CSVD group, the thalamic volume and cortex thickness in pars triangularis, rostral middle frontal and superior frontal were found significantly correlated with both HAMD and HAMA test scores. It suggests the pathway of the thalamus regulating emotion changes with the development of CSVD.

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