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Abstract #3018

Characterising the Common Wiring of the Human Brain

Mai Phuong Ho1, Fernando Calamante1,2,3, and Jinglei Lv1,2
1School of Biomedical Engineering, University of Sydney, Sydney, Australia, 2Brain and Mind Centre, University of Sydney, Sydney, Australia, 3Sydney Imaging, University of Sydney, Sydney, Australia


To compare white matter fibre tracks between individuals or within the same individual over time, a diffusion MRI tractography template is essential. Tractography template describes the location and orientation of fibre bundles that build a representative organization of human white matter. Despite numerous recent advances in methods to map human brain connectivity, tractography suffers from several limitations, including the over- and the under-representation of certain fibre populations. By integrating multimodal registration and SIFT2 quantification approach, we explore the most consistent bundles across subjects, which could help us advance our understanding of the common wiring in the human brain.

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